Chromosomal abnormalities in Hodgkin's disease

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Chromosomal abnormalities in Hodgkin's disease.

Numerous neoplastic states have associated or causal cytogenetic abnormalities. In some cancers, specific chromosomal abnormalities appear to correlate with the clinical characteristics and prognosis. Cytogenetic analysis of Hodgkin's disease is thought to be technically difficult and only a small number of cases with evaluable results have been reported. We have attempted cytogenetic studies o...

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Chromosomal Abnormalities: Genetic Disease Burden in India

Chromosomal abnormalities are frequent events. Globally, at least 7.6 million children are born annually with severe genetic or congenital malformations. Precise prevalence data are difficult to collect, especially in India, owing to great diversity of conditions and also because many cases remain undiagnosed. Genetic and congenital abnormality is the second most common cause of infant and chil...

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Chromosomal abnormalities and congenital heart disease.

In this study the authors attempted to determine the frequency of the classical chromosomal syndromes as a cause of congenital heart disease and sought other cytogenetic abnormalities in patients with congenital heart disease, selected either for the presence of extracardiac abnormalities or the existence of congenital heart disease in other members of the family. Of the 275 patients whose kary...

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Chromosomal Abnormalities and Congenital Heart Disease

In this study the authors attempted to determine the frequency of the classical chromosomal syndromes as a cause of congenital heart disease and sought other cytogenetic abnormalities in patients with congenital heart disease, selected either for the presence of extracardiac abnormalities or the existence of congenital heart disease in other members of the family. Of the 275 patients whose kary...

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Chromosomal Abnormalities in Patients with Congenital Heart Disease

BACKGROUND Chromosomal abnormalities (CAs) are an important cause of congenital heart disease (CHD). OBJECTIVE Determine the frequency, types and clinical characteristics of CAs identified in a sample of prospective and consecutive patients with CHD. METHOD Our sample consisted of patients with CHD evaluated during their first hospitalization in a cardiac intensive care unit of a pediatric ...

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ژورنال

عنوان ژورنال: Blood

سال: 1989

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v73.8.2149.2149